30.05.2026 20:45<\/p>\n\n\n\n
Bilim insanlar\u0131n\u0131n geli\u015ftirdi\u011fi yeni bir genetik test hangi hastalar\u0131n kemoterapiden ger\u00e7ekten fayda g\u00f6rece\u011fini belirleyebiliyor.<\/p>\n\n\n\n
Meme kanseri tedavisinde kullan\u0131lan yeni bir genetik testin sonu\u00e7lar\u0131, milyonlarca kad\u0131n\u0131n kemoterapi almadan g\u00fcvenli \u015fekilde tedavi edilebilece\u011fini ortaya koydu. Uzmanlar, bulgular\u0131n d\u00fcnya genelindeki tedavi k\u0131lavuzlar\u0131n\u0131 de\u011fi\u015ftirebilecek nitelikte oldu\u011funu belirtiyor.<\/p>\n\n\n\n
The Guardian’da yer alan habere g\u00f6re, d\u00fcnyada en yayg\u0131n kanser t\u00fcrlerinden biri olan meme kanserinde tedavi genellikle t\u00fcm\u00f6r\u00fcn cerrahi olarak \u00e7\u0131kar\u0131lmas\u0131n\u0131n ard\u0131ndan uygulan\u0131yor. Hastal\u0131\u011f\u0131n tekrar etme riski g\u00f6r\u00fclen vakalarda ise kemoterapi \u00f6neriliyor. Ancak kemoterapi; sa\u00e7 d\u00f6k\u00fclmesi, mide bulant\u0131s\u0131, yorgunluk, uyku sorunlar\u0131 ve cilt problemleri gibi ciddi yan etkilere yol a\u00e7abiliyor. Baz\u0131 hastalarda k\u0131s\u0131rl\u0131k, erken menopoz veya bili\u015fsel sorunlar gibi kal\u0131c\u0131 etkiler de g\u00f6r\u00fclebiliyor.<\/p>\n\n\n\n
Bilim insanlar\u0131n\u0131n geli\u015ftirdi\u011fi yeni genetik test ise hangi hastalar\u0131n kemoterapiden ger\u00e7ekten fayda g\u00f6rece\u011fini belirleyebiliyor. B\u00f6ylece baz\u0131 hastalar gereksiz kemoterapiden ka\u00e7\u0131n\u0131rken, tedavinin etkinli\u011finden de \u00f6d\u00fcn verilmemesi hedefleniyor.<\/p>\n\n\n\n
Sonu\u00e7lar\u0131 ABD’nin Chicago kentinde d\u00fczenlenen Amerikan Klinik Onkoloji Derne\u011fi (ASCO) y\u0131ll\u0131k toplant\u0131s\u0131nda a\u00e7\u0131klanan Optima adl\u0131 uluslararas\u0131 \u00e7al\u0131\u015fma, \u0130ngiltere \u00f6nc\u00fcl\u00fc\u011f\u00fcnde y\u00fcr\u00fct\u00fcld\u00fc.<\/p>\n\n\n\n
\u00c7al\u0131\u015fmada \u0130ngiltere, Norve\u00e7, \u0130sve\u00e7, Avustralya, Yeni Zelanda ve Tayland’dan yeni meme kanseri te\u015fhisi alm\u0131\u015f 4 bin 429 hasta takip edildi. Ara\u015ft\u0131rmaya kat\u0131lan hastalar\u0131n tamam\u0131 40 ya\u015f ve \u00fczerindeydi ve hormon resept\u00f6r\u00fc pozitif meme kanseri tan\u0131s\u0131 alm\u0131\u015ft\u0131. Bu kanser t\u00fcr\u00fc, t\u00fcm meme kanseri vakalar\u0131n\u0131n yakla\u015f\u0131k y\u00fczde 80’ini olu\u015fturuyor.<\/p>\n\n\n\n
Ara\u015ft\u0131rmada kullan\u0131lan Prosigna adl\u0131 test, t\u00fcm\u00f6r dokusundaki 50 genin aktivitesini analiz ederek kanserin \u00f6n\u00fcm\u00fczdeki 10 y\u0131l i\u00e7inde tekrarlama riskini hesapl\u0131yor. Elde edilen sonu\u00e7lar, kemoterapinin gerekli olup olmad\u0131\u011f\u0131 konusunda doktorlara yol g\u00f6steriyor.<\/p>\n\n\n\n
\u00c7al\u0131\u015fmaya kat\u0131lan hastalar iki gruba ayr\u0131ld\u0131. \u0130lk gruptaki hastalar standart tedavi kapsam\u0131nda kemoterapi ve ard\u0131ndan hormon tedavisi ald\u0131. \u0130kinci grupta ise t\u00fcm\u00f6rler genetik testle analiz edildi.<\/p>\n\n\n\n
Test sonucu y\u00fcksek riskli \u00e7\u0131kan hastalara kemoterapi ve hormon tedavisi uygulan\u0131rken, d\u00fc\u015f\u00fck risk grubundakiler yaln\u0131zca hormon tedavisi ald\u0131. Her iki grupta da gerekli g\u00f6r\u00fclen radyoterapi ve di\u011fer tedaviler standart \u015fekilde s\u00fcrd\u00fcr\u00fcld\u00fc.<\/p>\n\n\n\n
Be\u015f y\u0131ll\u0131k takip sonu\u00e7lar\u0131na g\u00f6re, genetik test sonucu d\u00fc\u015f\u00fck riskli olan hastalarda kemoterapi uygulanmas\u0131n\u0131n ek bir fayda sa\u011flamad\u0131\u011f\u0131 g\u00f6r\u00fcld\u00fc. Kemoterapi ve hormon tedavisi alanlar\u0131n y\u00fczde 95’i be\u015f y\u0131l sonra hayatta ve kansersizken, yaln\u0131zca hormon tedavisi alanlarda bu oran y\u00fczde 94 olarak \u00f6l\u00e7\u00fcld\u00fc.<\/p>\n\n\n\n
Ara\u015ft\u0131rmac\u0131lar, bu sonucun d\u00fc\u015f\u00fck riskli hastalar\u0131n kemoterapiye ba\u011fl\u0131 yan etkilere maruz kalmadan g\u00fcvenli \u015fekilde tedavi edilebilece\u011fini g\u00f6sterdi\u011fini belirtiyor.<\/p>\n\n\n\n
\u00c7al\u0131\u015fman\u0131n ba\u015f ara\u015ft\u0131rmac\u0131s\u0131 ve University College London Meme Onkolojisi Profes\u00f6r\u00fc Rob Stein, sonu\u00e7lar\u0131n meme kanseri tedavisinde uzun s\u00fcredir devam eden \u00f6nemli bir soruna \u00e7\u00f6z\u00fcm sundu\u011funu s\u00f6yledi.<\/p>\n\n\n\n
Stein, “Bulgular\u0131m\u0131z, bir\u00e7ok hastan\u0131n tedavi sonu\u00e7lar\u0131ndan \u00f6d\u00fcn vermeden kemoterapiden g\u00fcvenle ka\u00e7\u0131nabilece\u011fini g\u00f6steriyor. Bu \u00e7al\u0131\u015fma, tedavi kararlar\u0131n\u0131n yaln\u0131zca klinik \u00f6zelliklere de\u011fil, t\u00fcm\u00f6r\u00fcn biyolojik yap\u0131s\u0131na g\u00f6re verilmesinin \u00f6nemini ortaya koyuyor” dedi.<\/p>\n\n\n\n
Ara\u015ft\u0131rman\u0131n e\u015f ba\u015f ara\u015ft\u0131rmac\u0131lar\u0131ndan Glasgow \u00dcniversitesi Meme Onkolojisi Profes\u00f6r\u00fc Iain MacPherson da sonu\u00e7lar\u0131n hormon duyarl\u0131 meme kanseri hastalar\u0131nda kemoterapi kullan\u0131m\u0131n\u0131 g\u00fcvenli bi\u00e7imde azaltabilecek g\u00fc\u00e7l\u00fc kan\u0131tlar sundu\u011funu belirtti.<\/p>\n\n\n\n
Uzmanlara g\u00f6re \u00e7al\u0131\u015fma, meme kanseri tedavisinde daha ki\u015fiselle\u015ftirilmi\u015f ve hedefe y\u00f6nelik yakla\u015f\u0131mlar\u0131n \u00f6n\u00fcn\u00fc a\u00e7arken, hem hastalar\u0131n ya\u015fam kalitesini art\u0131rabilir hem de sa\u011fl\u0131k sistemlerinin kaynaklar\u0131n\u0131 daha verimli kullanmas\u0131na katk\u0131 sa\u011flayabilir.<\/p>\n\n\n\n
![<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"30.05.2026 20:45 Bilim insanlar\u0131n\u0131n geli\u015ftirdi\u011fi yeni bir genetik test hangi hastalar\u0131n kemoterapiden ger\u00e7ekten fayda g\u00f6rece\u011fini belirleyebiliyor. Meme kanseri tedavisinde kullan\u0131lan yeni bir genetik testin sonu\u00e7lar\u0131, milyonlarca kad\u0131n\u0131n kemoterapi almadan g\u00fcvenli \u015fekilde tedavi edilebilece\u011fini ortaya koydu. Uzmanlar, bulgular\u0131n d\u00fcnya genelindeki tedavi k\u0131lavuzlar\u0131n\u0131 de\u011fi\u015ftirebilecek nitelikte oldu\u011funu belirtiyor. The Guardian’da yer alan habere g\u00f6re, d\u00fcnyada en yayg\u0131n kanser…<\/p>\n","protected":false},"author":5,"featured_media":10120,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[12],"tags":[637],"class_list":["post-10119","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik","tag-kemoterapi"],"jetpack_featured_media_url":"https:\/\/dbsnewsmedia.com\/wp-content\/uploads\/2026\/05\/48.jpg","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/posts\/10119","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=10119"}],"version-history":[{"count":1,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/posts\/10119\/revisions"}],"predecessor-version":[{"id":10121,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/posts\/10119\/revisions\/10121"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/media\/10120"}],"wp:attachment":[{"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=10119"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=10119"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=10119"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}](\"https:\/\/i.gazeteoksijen.com\/storage\/files\/images\/2025\/04\/09\/meme-kanserine-karsi-akilli-bomba-bbqp.jpg\"){kind=link}