{"id":1423,"date":"2026-03-03T18:23:02","date_gmt":"2026-03-03T15:23:02","guid":{"rendered":"https:\/\/dbsnewsmedia.com\/?p=1423"},"modified":"2026-03-03T18:23:02","modified_gmt":"2026-03-03T15:23:02","slug":"kanserle-mucadelede-yeni-umut-kedilerden-insanlara-genetik-isik","status":"publish","type":"post","link":"https:\/\/dbsnewsmedia.com\/?p=1423","title":{"rendered":"Kanserle M\u00fccadelede Yeni Umut: Kedilerden \u0130nsanlara Genetik I\u015f\u0131k"},"content":{"rendered":"\n

Kanser Ara\u015ft\u0131rmalar\u0131nda Yeni D\u00f6nem: Kedilerle \u0130nsanlar\u0131n Genetik Ortakl\u0131\u011f\u0131<\/strong><\/p>\n\n\n\n

T\u0131p ve veterinerlik d\u00fcnyas\u0131, kanserle m\u00fccadelede g\u00fc\u00e7lerini birle\u015ftirdi. Wellcome Sanger Enstit\u00fcs\u00fc<\/strong> \u00f6nderli\u011finde y\u00fcr\u00fct\u00fclen ve be\u015f farkl\u0131 \u00fclkeden 500 evcil kedinin kat\u0131ld\u0131\u011f\u0131 dev ara\u015ft\u0131rma, onkoloji alan\u0131nda yeni bir d\u00f6nemin kap\u0131s\u0131n\u0131 aralad\u0131.<\/p>\n\n\n\n

Ortak Riskler, Ortak Umut: Kedilerden Kanserin Genetik \u015eifresine Yolculuk<\/strong><\/p>\n\n\n\n

Ara\u015ft\u0131rman\u0131n en dikkat \u00e7ekici bulgular\u0131ndan biri, evcil kedilerin insanlarla ayn\u0131 ya\u015fam alanlar\u0131n\u0131 payla\u015fmas\u0131n\u0131n kanser riskini nas\u0131l \u015fekillendirdi\u011fi \u00fczerine oldu. Ontario Veteriner Koleji’nden Profes\u00f6r Geoffrey Wood, kedilerin insanlarla ayn\u0131 \u00e7evresel fakt\u00f6rlere maruz kald\u0131\u011f\u0131n\u0131 vurgulayarak, bu durumun kanser geli\u015fim s\u00fcre\u00e7lerini birbirine yakla\u015ft\u0131rd\u0131\u011f\u0131n\u0131 ifade ediyor.<\/p>\n\n\n\n

Yap\u0131lan DNA dizileme \u00e7al\u0131\u015fmalar\u0131, kedilerdeki t\u00fcm\u00f6r geli\u015fimini tetikleyen genetik mekanizmalar\u0131n, insanlardaki kanser h\u00fccrelerinin davran\u0131\u015flar\u0131yla b\u00fcy\u00fck oranda benzerlik g\u00f6sterdi\u011fini kan\u0131tl\u0131yor. Bu benzerlik, bilim insanlar\u0131na kanserin nas\u0131l geli\u015fti\u011fi ve \u00e7evresel etkilerin bu s\u00fcre\u00e7te nas\u0131l bir rol oynad\u0131\u011f\u0131 konusunda daha net veriler sunuyor.<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Kanser Ara\u015ft\u0131rmalar\u0131nda Kritik \u0130kili: FBXW7 ve PIK3CA<\/strong><\/h3>\n\n\n\n

Ara\u015ft\u0131rmac\u0131lar, kedi ve insan kanserleri aras\u0131ndaki k\u00f6pr\u00fcy\u00fc kuran yedi temel “s\u00fcr\u00fcc\u00fc gen” tan\u0131mlad\u0131. \u0130ncelenen kedi t\u00fcm\u00f6rlerinin y\u00fczde 50\u2019sinden fazlas\u0131nda saptanan “FBXW7<\/strong>” geni, \u00e7al\u0131\u015fman\u0131n merkezine yerle\u015fti. \u0130nsanlarda meme kanserinin seyrini a\u011f\u0131rla\u015ft\u0131ran bu genetik de\u011fi\u015fikli\u011fin kedilerde de bu denli yayg\u0131n olmas\u0131, iki t\u00fcr aras\u0131ndaki biyolojik ortakl\u0131\u011f\u0131 g\u00f6zler \u00f6n\u00fcne seriyor. <\/p>\n\n\n\n

Ayr\u0131ca insanlarda hedefe y\u00f6nelik tedavilerle bask\u0131lanan “PIK3CA” geninin, kedilerdeki t\u00fcm\u00f6rlerin y\u00fczde 47’sinde de bulundu\u011fu saptand\u0131. Bu bulgu, insanlarda ba\u015far\u0131yla uygulanan ila\u00e7lar\u0131n veteriner onkolojisinde de kullan\u0131labilece\u011fi umudunu do\u011furdu.<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Onkolojide Yeni D\u00f6nem: \u201cTek T\u0131p\u201d Yakla\u015f\u0131m\u0131 \u00d6ne \u00c7\u0131k\u0131yor<\/strong><\/p>\n\n\n\n

“Tek T\u0131p” (One Medicine) olarak adland\u0131r\u0131lan vizyon \u00e7er\u00e7evesinde, t\u0131bbi ve veterinerlik verilerinin kar\u015f\u0131l\u0131kl\u0131 payla\u015f\u0131m\u0131 hedefleniyor. Dr. Louise Van Der Weyden, bu \u00e7al\u0131\u015fmay\u0131 kedi onkolojisindeki en b\u00fcy\u00fck geli\u015fmelerden biri olarak nitelendirerek, kedilerdeki t\u00fcm\u00f6r geneti\u011finin art\u0131k bir “kara kutu” olmaktan \u00e7\u0131kt\u0131\u011f\u0131n\u0131 belirtti. Bu veriler \u0131\u015f\u0131\u011f\u0131nda, insanlardaki ba\u015far\u0131l\u0131 tedavi yakla\u015f\u0131mlar\u0131n\u0131n kedilerde, kedilerdeki g\u00f6zlemlerin ise insanlardaki klinik \u00e7al\u0131\u015fmalarda kullan\u0131lmas\u0131 planlan\u0131yor. <\/p>\n\n\n\n

Bilim insanlar\u0131, hassas onkoloji y\u00f6ntemleri sayesinde gelecekte kanser te\u015fhis ve tedavisinde her iki t\u00fcr i\u00e7in de daha etkili ve g\u00fcvenli yollar\u0131n bulunaca\u011f\u0131n\u0131 \u00f6ng\u00f6r\u00fcyor.<\/p>\n\n\n\n

03.03.2026 18:23<\/p>\n\n\n\n

Kaynak:https:\/\/www.cumhuriyet.com.tr\/yasam\/kanserle-mucadelede-patili-isbirligi-kedilerdeki-genetik-sifre-insanlara-umut-olacak-2483554<\/a><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Kanser Ara\u015ft\u0131rmalar\u0131nda Yeni D\u00f6nem: Kedilerle \u0130nsanlar\u0131n Genetik Ortakl\u0131\u011f\u0131 T\u0131p ve veterinerlik d\u00fcnyas\u0131, kanserle m\u00fccadelede g\u00fc\u00e7lerini birle\u015ftirdi. Wellcome Sanger Enstit\u00fcs\u00fc \u00f6nderli\u011finde y\u00fcr\u00fct\u00fclen ve be\u015f farkl\u0131 \u00fclkeden 500 evcil kedinin kat\u0131ld\u0131\u011f\u0131 dev ara\u015ft\u0131rma, onkoloji alan\u0131nda yeni bir d\u00f6nemin kap\u0131s\u0131n\u0131 aralad\u0131. Ortak Riskler, Ortak Umut: Kedilerden Kanserin Genetik \u015eifresine Yolculuk Ara\u015ft\u0131rman\u0131n en dikkat \u00e7ekici bulgular\u0131ndan biri, evcil kedilerin insanlarla ayn\u0131…<\/p>\n","protected":false},"author":4,"featured_media":1426,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[2],"tags":[256,254],"class_list":["post-1423","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-yasam","tag-kanser","tag-kedi"],"jetpack_featured_media_url":"https:\/\/dbsnewsmedia.com\/wp-content\/uploads\/2026\/03\/6bce17a8-a0e6-49d9-abec-a3218991e345.jpg","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/posts\/1423","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1423"}],"version-history":[{"count":1,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/posts\/1423\/revisions"}],"predecessor-version":[{"id":1427,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/posts\/1423\/revisions\/1427"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/media\/1426"}],"wp:attachment":[{"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1423"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1423"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1423"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}