24.03.2026 17:37<\/p>\n\n\n\n
N\u00f6robilim ve N\u00f6roteknoloji M\u00fckemmeliyet Ortak Uygulama ve Ara\u015ft\u0131rma Merkezi (N\u00d6ROM) taraf\u0131ndan y\u00fcr\u00fct\u00fclen \u00e7al\u0131\u015fmayla migrenin yaln\u0131zca ba\u015f a\u011fr\u0131s\u0131yla s\u0131n\u0131rl\u0131 olmad\u0131\u011f\u0131, beyindeki g\u00f6rsel i\u015flemleme ve a\u011fr\u0131 mekanizmalar\u0131yla yak\u0131ndan ili\u015fkili oldu\u011fu ortaya konuldu<\/p>\n\n\n\n
Y\u00fcksek\u00f6\u011fretim Kurulu (Y\u00d6K) taraf\u0131ndan yap\u0131lan a\u00e7\u0131klamaya g\u00f6re, N\u00d6ROM b\u00fcnyesinde y\u00fcr\u00fct\u00fclen ve Ankara \u00dcniversitesi ara\u015ft\u0131rmac\u0131lar\u0131n\u0131n katk\u0131 sa\u011flad\u0131\u011f\u0131 \u00e7al\u0131\u015fma, n\u00f6robilim alan\u0131n\u0131n sayg\u0131n dergilerinden The Journal of Headache and Pain\u2019de yay\u0131mland\u0131.<\/p>\n\n\n\n
\u00c7al\u0131\u015fmada, migrenin yaln\u0131zca ba\u015f a\u011fr\u0131s\u0131yla s\u0131n\u0131rl\u0131 olmad\u0131\u011f\u0131, beyindeki g\u00f6rsel i\u015flemleme ve a\u011fr\u0131 mekanizmalar\u0131yla yak\u0131ndan ili\u015fkili oldu\u011fu T\u00fcrkiye\u2019de ger\u00e7ekle\u015ftirilen n\u00f6rog\u00f6r\u00fcnt\u00fcleme \u00e7al\u0131\u015fmalar\u0131yla ortaya kondu. Bulgular, migrenli bireylerin tekrarlayan g\u00f6rsel uyaranlara kar\u015f\u0131 al\u0131\u015fma (habit\u00fcasyon) geli\u015ftiremedi\u011fini ve bu uyaranlar\u0131n beyin taraf\u0131ndan s\u00fcrekli \u201c\u00f6nemli\u201d olarak kodland\u0131\u011f\u0131n\u0131 g\u00f6sterdi.<\/p>\n\n\n\n
Ara\u015ft\u0131rma kapsam\u0131nda 30\u2019u migren hastas\u0131, 29\u2019u sa\u011fl\u0131kl\u0131 olmak \u00fczere toplam 59 kad\u0131n kat\u0131l\u0131mc\u0131 incelendi. Kat\u0131l\u0131mc\u0131lar atak d\u00f6neminde olmamalar\u0131na ra\u011fmen, migrenli bireylerin g\u00f6rsel uyaranlara kar\u015f\u0131 sa\u011fl\u0131kl\u0131 bireylerden farkl\u0131 beyin tepkileri verdi\u011fi tespit edildi.<\/p>\n\n\n\n
A\u00e7\u0131klamada g\u00f6r\u00fc\u015flerine yer verilen N\u00d6ROM M\u00fcd\u00fcr\u00fc Prof. Dr. Hayrunnisa Bolay Belen, ara\u015ft\u0131rma sonucu ortaya \u00e7\u0131kan bulgular\u0131n literat\u00fcrde ilk kez ortaya kondu\u011funu belirtti.<\/p>\n\n\n\n
Normal insan beyninde tekrarlayan uyar\u0131 geldi\u011finde beynin buna verdi\u011fi tepkiyi azaltt\u0131\u011f\u0131na dikkati \u00e7eken Belen, migrenli beynin normal beynin aksine tepkiyi giderek art\u0131rmaya ba\u015flad\u0131\u011f\u0131n\u0131 ifade etti.<\/p>\n\n\n\n
Bu art\u0131\u015f\u0131n g\u00f6rsel i\u015flemenin yap\u0131ld\u0131\u011f\u0131 beynin arka k\u0131sm\u0131nda de\u011fil, aksine beynin en \u00f6n k\u0131sm\u0131nda bulunan ve \u00fcst d\u00fczey kontrol merkezi olan orbitofrontal b\u00f6lgede ger\u00e7ekle\u015fmesinin son derece \u00f6nemli oldu\u011funu aktaran Belen, “Buras\u0131 g\u00f6rmenin \u00fcst d\u00fczey kontrol merkezi ve ayn\u0131 zamanda da gelen uyar\u0131ya zararl\u0131, faydal\u0131 ya da duygusal bir de\u011fer bi\u00e7en yer” bilgisini verdi.<\/p>\n\n\n\n
\u00c7al\u0131\u015fmayla migrenli beyinde tekrarlayan uyaranlar\u0131n filtrelenemedi\u011fini ve do\u011frudan a\u011fr\u0131 mekanizmalar\u0131yla ili\u015fkilendirildi\u011fini ilk kez g\u00f6stermi\u015f olduklar\u0131n\u0131n alt\u0131n\u0131 \u00e7izen Belen, “Sorun, tekrarlayan uyar\u0131lar\u0131n gereksiz ya da \u00f6nemsiz olan uyar\u0131y\u0131 filtreleme sisteminde bir problem gibi g\u00f6r\u00fcn\u00fcyor ve de ilk kez beynin \u00f6n k\u0131sm\u0131nda da bununla ilgili bir yerin yer ald\u0131\u011f\u0131n\u0131 g\u00f6r\u00fcyoruz. Bunu biz kan\u0131tlad\u0131k” a\u00e7\u0131klamas\u0131n\u0131 yapt\u0131.<\/p>\n\n\n\n
Belen, \u00e7al\u0131\u015fman\u0131n deney a\u015famas\u0131nda, migrenli ve migrensiz kat\u0131l\u0131mc\u0131lar\u0131n g\u00fcnl\u00fck hayatta kar\u015f\u0131la\u015ft\u0131klar\u0131 sorunlara benzer g\u00f6revler vererek MR cihaz\u0131ndan bulgular elde ettiklerini vurgulad\u0131.<\/p>\n\n\n\n
Migren hastalar\u0131n\u0131n ya\u015fam kalitesinin art\u0131r\u0131lmas\u0131 i\u00e7in marketlerde ya da al\u0131\u015fveri\u015f merkezlerindeki \u0131\u015f\u0131klar\u0131n \u015fiddetinin azalt\u0131labilece\u011fi \u00f6nerisinde bulunan Belen, “Buralardaki yatay \u00e7izgiler ya da \u00e7izgili olan \u0131\u015f\u0131klar\u0131n rahats\u0131z etti\u011fini migrenli hastalar \u00f6zellikle s\u00f6yl\u00fcyor. Burada bir de\u011fi\u015fim ba\u015flat\u0131labilir. Bunlar toplumun tamam\u0131n\u0131n huzuru i\u00e7in \u00f6nemli” ifadelerini kulland\u0131.<\/p>\n\n\n\n
Ara\u015ft\u0131rman\u0131n y\u00fcr\u00fct\u00fcc\u00fclerinden Ankara \u00dcniversitesi T\u0131p Fak\u00fcltesi Fizyoloji Anabilim Dal\u0131 \u00d6\u011fretim \u00dcyesi Dr. Serta\u00e7 \u00dcst\u00fcn ise migrenin duyusal i\u015fleme boyutuna dikkati \u00e7ekerek, “Migren sadece bir ba\u015f a\u011fr\u0131s\u0131 hastal\u0131\u011f\u0131 olarak d\u00fc\u015f\u00fcn\u00fclebiliyor ama migrende \u00e7e\u015fitli g\u00f6rsel uyaranlar\u0131n rahats\u0131zl\u0131k verdi\u011fi, farkl\u0131 \u015fekillerde alg\u0131land\u0131\u011f\u0131 hastalar taraf\u0131ndan rapor ediliyor” bilgisini payla\u015ft\u0131.<\/p>\n\n\n\n
Doktora sonras\u0131 ara\u015ft\u0131rmac\u0131 Dr. \u0130lkem G\u00fczel de alt d\u00fczey g\u00f6rsel i\u015flemleme b\u00f6lgelerinin do\u011frudan a\u011fr\u0131 b\u00f6lgesiyle ili\u015fkili oldu\u011funu tespit ettiklerini belirterek, bu bulgunun migren hastalar\u0131nda \u0131\u015f\u0131\u011fa duyarl\u0131l\u0131\u011f\u0131 a\u00e7\u0131klamaya yard\u0131mc\u0131 oldu\u011funu ifade etti.<\/p>\n\n\n\n
Ara\u015ft\u0131rmada g\u00f6rev alan doktora \u00f6\u011frencisi Ceren Onlat ise migren hastalar\u0131n\u0131n s\u0131kl\u0131kla rahats\u0131zl\u0131k duydu\u011fu g\u00f6rsel uyaranlar\u0131n laboratuvar ortam\u0131nda ger\u00e7ek hayatla ili\u015fkilendirilerek kullan\u0131ld\u0131\u011f\u0131n\u0131 ve ara\u015ft\u0131rman\u0131n ekolojik ge\u00e7erlili\u011fini art\u0131racak bir deney tasar\u0131m\u0131 geli\u015ftirildi\u011fini kaydetti.<\/p>\n\n\n\n