{"id":4052,"date":"2026-03-28T19:32:51","date_gmt":"2026-03-28T16:32:51","guid":{"rendered":"https:\/\/dbsnewsmedia.com\/?p=4052"},"modified":"2026-03-28T19:33:30","modified_gmt":"2026-03-28T16:33:30","slug":"hafiza-kaybi-beklemeden-alzheimeri-yakalayan-yeni-test","status":"publish","type":"post","link":"https:\/\/dbsnewsmedia.com\/?p=4052","title":{"rendered":"Haf\u0131za kayb\u0131 beklemeden Alzheimer\u2019\u0131 yakalayan yeni test"},"content":{"rendered":"\n

Alzheimer hastal\u0131\u011f\u0131n\u0131n erken te\u015fhisi, t\u0131bb\u0131n en zorlay\u0131c\u0131 alanlar\u0131ndan biri olmay\u0131 s\u00fcrd\u00fcr\u00fcrken bilim insanlar\u0131 dikkat \u00e7ekici bir geli\u015fmeye imza att\u0131. Geli\u015ftirilen yeni bir burun s\u00fcr\u00fcnt\u00fcs\u00fc testi, d\u00fc\u015f\u00fcnme ve haf\u0131za sorunlar\u0131 hen\u00fcz ortaya \u00e7\u0131kmadan hastal\u0131\u011f\u0131n erken belirtilerini tespit edebilecek potansiyel sunuyor. Uzmanlara g\u00f6re bu y\u00f6ntemin do\u011frulanmas\u0131 halinde, Alzheimer\u2019\u0131n beyinde ciddi hasar olu\u015fmadan \u00f6nce belirlenmesi m\u00fcmk\u00fcn hale gelebilir.<\/strong><\/p>\n\n\n\n

Alzheimer, haf\u0131zay\u0131, d\u00fc\u015f\u00fcnme becerilerini ve g\u00fcnl\u00fck ya\u015fam\u0131 s\u00fcrd\u00fcrme kapasitesini zaman i\u00e7inde zay\u0131flatan ilerleyici bir hastal\u0131k. Ancak hastal\u0131k \u00e7o\u011fu zaman belirtiler belirgin hale geldikten sonra fark ediliyor. Bu da tedavi ve m\u00fcdahale a\u00e7\u0131s\u0131ndan zaman kayb\u0131na yol a\u00e7abiliyor.<\/p>\n\n\n\n

Yeni geli\u015ftirilen testin dikkat \u00e7ekmesinin nedeni de tam burada ortaya \u00e7\u0131k\u0131yor: Beyindeki hasar b\u00fcy\u00fcmeden \u00f6nce alarm verebilmesi.<\/p>\n\n\n\n

Burun i\u00e7inden al\u0131nan \u00f6rnek \u00fczerinde analiz yap\u0131ld\u0131<\/h2>\n\n\n\n

Ara\u015ft\u0131rmada bilim insanlar\u0131, burnun \u00fcst b\u00f6l\u00fcm\u00fcnden olduk\u00e7a nazik bir s\u00fcr\u00fcnt\u00fc y\u00f6ntemiyle koku alg\u0131s\u0131yla ba\u011flant\u0131l\u0131 sinir h\u00fccrelerini toplad\u0131. Daha sonra bu h\u00fccreler laboratuvarda incelendi.<\/p>\n\n\n\n

\u00c7al\u0131\u015fmada toplam 22 kat\u0131l\u0131mc\u0131n\u0131n \u00f6rnekleri kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131. Bunlar aras\u0131nda hen\u00fcz belirgin \u015fikayeti olmayan ama laboratuvar bulgular\u0131nda erken i\u015faretler ta\u015f\u0131yan ki\u015filer de yer ald\u0131.<\/p>\n\n\n\n

Elde edilen sonu\u00e7larda, erken evre Alzheimer riski ta\u015f\u0131yan ya da hastal\u0131k tan\u0131s\u0131 alm\u0131\u015f ki\u015filerle sa\u011fl\u0131kl\u0131 bireyler aras\u0131nda belirgin farkl\u0131l\u0131klar g\u00f6r\u00fcld\u00fc. Ara\u015ft\u0131rmac\u0131lar, bu testin yaln\u0131zca dolayl\u0131 i\u015faretlere de\u011fil, canl\u0131 sinir ve ba\u011f\u0131\u015f\u0131kl\u0131k sistemi faaliyetlerine bakmas\u0131 nedeniyle ayr\u0131 bir \u00f6nem ta\u015f\u0131d\u0131\u011f\u0131n\u0131 d\u00fc\u015f\u00fcn\u00fcyor.<\/p>\n\n\n\n

Uzmanlar\u0131n vurgulad\u0131\u011f\u0131 nokta \u015fu: Bug\u00fcn kullan\u0131lan baz\u0131 kan testleri Alzheimer ile ili\u015fkili i\u015faretleri g\u00f6sterebiliyor, ancak bunlar\u0131n bir k\u0131sm\u0131 daha ge\u00e7 d\u00f6nemde ortaya \u00e7\u0131kan de\u011fi\u015fiklikleri yakal\u0131yor. Yeni burun testi ise hastal\u0131kla ba\u011flant\u0131l\u0131 de\u011fi\u015fimlere daha erken ve daha do\u011frudan bakma ihtimali sunuyor.<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Koku duyusundaki azalma y\u0131llar \u00f6ncesine dayanabiliyor<\/h2>\n\n\n\n

Ara\u015ft\u0131rman\u0131n en dikkat \u00e7ekici y\u00f6nlerinden biri, koku alma duyusuyla Alzheimer aras\u0131ndaki ili\u015fkiye dayanmas\u0131. Uzmanlara g\u00f6re koku kayb\u0131, bunama belirtileri ortaya \u00e7\u0131kmadan y\u0131llar \u00f6nce g\u00f6r\u00fclebilen \u00f6nemli i\u015faretlerden biri olabiliyor. Hatta baz\u0131 vakalarda bu de\u011fi\u015fimin, di\u011fer belirtilerden yakla\u015f\u0131k 10 y\u0131l \u00f6nce ortaya \u00e7\u0131kabildi\u011fi belirtiliyor.<\/p>\n\n\n\n

Bu nedenle burnun i\u00e7 k\u0131sm\u0131ndaki koku alg\u0131layan sinir dokusunun incelenmesi, Alzheimer riskini \u00e7ok daha erken d\u00f6nemde anlamak i\u00e7in yeni bir pencere a\u00e7abilir.<\/p>\n\n\n\n

Ara\u015ft\u0131rmac\u0131lar da bug\u00fcne kadar hastal\u0131k hakk\u0131nda elde edilen bilgilerin \u00f6nemli b\u00f6l\u00fcm\u00fcn\u00fcn otopsi dokular\u0131ndan geldi\u011fini, \u015fimdi ise ya\u015fayan sinir dokusunu inceleyebilmenin tan\u0131 ve tedavi a\u00e7\u0131s\u0131ndan yeni kap\u0131lar a\u00e7abilece\u011fini s\u00f6yl\u00fcyor.<\/p>\n\n\n\n

Alzheimer\u2019da \u00f6zellikle tau ve amiloid beta ad\u0131 verilen proteinlerin beyinde anormal \u015fekilde birikmesi b\u00fcy\u00fck \u00f6nem ta\u015f\u0131yor. Bu birikimler sinir h\u00fccrelerinin i\u015fleyi\u015fini bozuyor ve zamanla hastal\u0131\u011f\u0131n ilerlemesine katk\u0131da bulunuyor.<\/p>\n\n\n\n

Son y\u0131llarda geli\u015ftirilen baz\u0131 biyobelirte\u00e7 testleri de bu proteinleri hedef al\u0131yor. Ancak yeni burun s\u00fcr\u00fcnt\u00fcs\u00fc testinin fark\u0131, hastal\u0131\u011f\u0131n canl\u0131 sinir dokusundaki etkilerini daha erken a\u015famada g\u00f6rebilme ihtimali.<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Hen\u00fcz yolun ba\u015f\u0131nda<\/strong><\/p>\n\n\n\n

Ara\u015ft\u0131rmac\u0131lar sonu\u00e7lar\u0131n umut verici oldu\u011funu s\u00f6ylese de, \u00e7al\u0131\u015fman\u0131n hen\u00fcz k\u00fc\u00e7\u00fck \u00f6l\u00e7ekli oldu\u011funun alt\u0131n\u0131 \u00e7iziyor. \u0130lk a\u015famada sadece 22 ki\u015fi \u00fczerinde yap\u0131lan bu ara\u015ft\u0131rman\u0131n daha b\u00fcy\u00fck gruplarda tekrarlanmas\u0131 gerekiyor. Bilim ekibi \u015fimdi hem daha geni\u015f kat\u0131l\u0131mc\u0131 gruplar\u0131yla \u00e7al\u0131\u015fmay\u0131 hem de bu testin zaman i\u00e7inde tedaviye verilen yan\u0131t\u0131 izleyip izleyemeyece\u011fini ara\u015ft\u0131rmay\u0131 planl\u0131yor.<\/p>\n\n\n\n

Yani bu yeni y\u00f6ntem \u015fimdilik kesinle\u015fmi\u015f bir rutin tarama testi de\u011fil. Ancak sonu\u00e7lar do\u011frulan\u0131rsa, Alzheimer<\/a>\u2019\u0131n erken te\u015fhisinde \u00f6nemli bir d\u00f6n\u00fcm noktas\u0131 olabilir. \u00c7\u00fcnk\u00fc uzmanlar\u0131n uzun s\u00fcredir ula\u015fmak istedi\u011fi hedef, hastal\u0131k ciddi haf\u0131za kayb\u0131na yol a\u00e7madan \u00f6nce risk alt\u0131ndaki ki\u015fileri belirleyebilmek.<\/p>\n\n\n\n

28.03.2026 19:32<\/p>\n\n\n\n

Kaynak:https:\/\/www.hurriyet.com.tr\/aile\/galeri-alzheimer-sonunda-tarih-mi-oluyor-hafiza-sorunlari-baslamadan-once-sinyal-verebilen-test-gelistirildi-43135865<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Alzheimer hastal\u0131\u011f\u0131n\u0131n erken te\u015fhisi, t\u0131bb\u0131n en zorlay\u0131c\u0131 alanlar\u0131ndan biri olmay\u0131 s\u00fcrd\u00fcr\u00fcrken bilim insanlar\u0131 dikkat \u00e7ekici bir geli\u015fmeye imza att\u0131. Geli\u015ftirilen yeni bir burun s\u00fcr\u00fcnt\u00fcs\u00fc testi, d\u00fc\u015f\u00fcnme ve haf\u0131za sorunlar\u0131 hen\u00fcz ortaya \u00e7\u0131kmadan hastal\u0131\u011f\u0131n erken belirtilerini tespit edebilecek potansiyel sunuyor. Uzmanlara g\u00f6re bu y\u00f6ntemin do\u011frulanmas\u0131 halinde, Alzheimer\u2019\u0131n beyinde ciddi hasar olu\u015fmadan \u00f6nce belirlenmesi m\u00fcmk\u00fcn hale gelebilir….<\/p>\n","protected":false},"author":4,"featured_media":4058,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[2],"tags":[1425],"class_list":["post-4052","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-yasam","tag-saglikalzheimeralzheimer-tedavisi"],"jetpack_featured_media_url":"https:\/\/dbsnewsmedia.com\/wp-content\/uploads\/2026\/03\/69c395265b06fcb7fa324b3e.webp","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/posts\/4052","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4052"}],"version-history":[{"count":2,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/posts\/4052\/revisions"}],"predecessor-version":[{"id":4060,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/posts\/4052\/revisions\/4060"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/media\/4058"}],"wp:attachment":[{"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4052"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=4052"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=4052"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}