{"id":6917,"date":"2026-04-21T21:25:20","date_gmt":"2026-04-21T18:25:20","guid":{"rendered":"https:\/\/dbsnewsmedia.com\/?p=6917"},"modified":"2026-04-21T21:25:20","modified_gmt":"2026-04-21T18:25:20","slug":"karnimizdaki-kucuk-rehberler-zihinsel-dejenerasyonun-izini-suruyor","status":"publish","type":"post","link":"https:\/\/dbsnewsmedia.com\/?p=6917","title":{"rendered":"Karn\u0131m\u0131zdaki K\u00fc\u00e7\u00fck Rehberler Zihinsel Dejenerasyonun \u0130zini S\u00fcr\u00fcyor"},"content":{"rendered":"\n

21.04.2026 21:25<\/p>\n\n\n\n

\u0130ngiltere merkezli akademik bir kurumun y\u00fcr\u00fctt\u00fc\u011f\u00fc incelemeler, sindirim sistemindeki mikrobiyolojik dizilimlerin, sinirsel tahribat hen\u00fcz g\u00f6zlemlenmeden \u00e7ok uzun zaman evvel bu duruma dair i\u015faretler verebilece\u011fini kan\u0131tlad\u0131.<\/strong><\/p>\n\n\n\n

Bilim insanlar\u0131, ba\u011f\u0131rsak bakterilerindeki belirgin kal\u0131plar\u0131n Parkinson hastal\u0131\u011f\u0131 belirtileri ortaya \u00e7\u0131kmadan y\u0131llar \u00f6nce bu hastal\u0131\u011fa yakalanma riski ta\u015f\u0131yan ki\u015fileri belirleyebilece\u011fini ke\u015ffetti.<\/p>\n\n\n\n

Kar\u0131n B\u00f6lgesi Refah\u0131, Zihinsel Fonksiyon Kay\u0131plar\u0131n\u0131n Seyrini Belirliyor<\/strong><\/p>\n\n\n\n

University College London (UCL) ara\u015ft\u0131rmac\u0131lar\u0131, hastal\u0131\u011fa sahip ki\u015filerin yan\u0131 s\u0131ra genetik olarak hastal\u0131\u011fa yatk\u0131n olanlar\u0131n farkl\u0131 ba\u011f\u0131rsak bakteri modelleri ta\u015f\u0131d\u0131\u011f\u0131n\u0131 buldu. UCL\u2019deki \u00e7al\u0131\u015fman\u0131n ba\u015f ara\u015ft\u0131rmac\u0131s\u0131 Anthony Schapira, \u201cSon y\u0131llarda, bir beyin bozuklu\u011fu olan Parkinson hastal\u0131\u011f\u0131 ile ba\u011f\u0131rsak sa\u011fl\u0131\u011f\u0131 aras\u0131ndaki ba\u011flant\u0131lar\u0131n giderek daha fazla fark\u0131na var\u0131ld\u0131\u201d dedi. \u00c7al\u0131\u015fman\u0131n mevcut kan\u0131tlar\u0131 g\u00fc\u00e7lendirdi\u011fini ve ba\u011f\u0131rsak mikroplar\u0131n\u0131n semptomlar ba\u015flamadan Parkinson riskinin erken uyar\u0131 sinyali olarak hizmet edebilece\u011fini g\u00f6sterdi\u011fini de ekledi.<\/p>\n\n\n\n

\u00c7al\u0131\u015fmaya Parkinson hastal\u0131\u011f\u0131 olan 271 ki\u015fi, hi\u00e7bir klinik semptomu olmayan, Parkinson hastal\u0131\u011f\u0131 riskini 30 kata kadar art\u0131rabilen bir gen varyant\u0131 olan GBA1 varyant\u0131n\u0131n 43 ta\u015f\u0131y\u0131c\u0131s\u0131 ve 150 sa\u011fl\u0131kl\u0131 kontrol kat\u0131l\u0131mc\u0131s\u0131 dahil edildi.<\/p>\n\n\n\n

Nature Medicine\u2019de yay\u0131nlanan sonu\u00e7lar, ba\u011f\u0131rsak mikrobiyomunu olu\u015fturan mikrobiyal t\u00fcrlerin d\u00f6rtte birinden fazlas\u0131n\u0131n Parkinson hastal\u0131\u011f\u0131 olan ki\u015filer ile sa\u011fl\u0131kl\u0131 kontrol kat\u0131l\u0131mc\u0131lar\u0131 aras\u0131nda farkl\u0131l\u0131k g\u00f6sterdi\u011fini ortaya koydu. Baz\u0131 mikroplar Parkinson hastal\u0131\u011f\u0131 olanlarda daha yayg\u0131n g\u00f6r\u00fcl\u00fcrken baz\u0131lar\u0131 da sa\u011fl\u0131kl\u0131 kat\u0131l\u0131mc\u0131lar aras\u0131nda yayg\u0131n g\u00f6r\u00fcld\u00fc. Ara\u015ft\u0131rmac\u0131lar bu modelin en \u00e7ok Parkinson hastal\u0131\u011f\u0131n\u0131n ileri evrelerindeki ki\u015filerde fark edildi\u011fini buldu.<\/p>\n\n\n\n

Bu mikroplar\u0131n \u00e7o\u011fu, sa\u011fl\u0131kl\u0131 kontroller ile hen\u00fcz hastal\u0131\u011f\u0131n herhangi bir semptomunu ya\u015famam\u0131\u015f GBA1 gen varyant\u0131na sahip ki\u015filerle kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda miktar a\u00e7\u0131s\u0131ndan da tutarl\u0131 bir \u015fekilde farkl\u0131l\u0131k g\u00f6sterdi.<\/p>\n\n\n\n

\u00c7al\u0131\u015fman\u0131n e\u015f yazarlar\u0131 aras\u0131nda olan Stanislav Dusko Ehrlich, \u201cBa\u011f\u0131rsak mikrobiyomu analizi, Parkinson hastal\u0131\u011f\u0131 geli\u015ftirme riski ta\u015f\u0131yan bireyleri belirlememizi ve b\u00f6ylece diyet d\u00fczenlemeleri gibi y\u00f6ntemlerle kendi risklerini azaltmalar\u0131na yard\u0131mc\u0131 olmam\u0131z\u0131 sa\u011flayabilir\u201d de\u011ferlendirmesinde bulundu.<\/p>\n\n\n\n

Yazarlar ayr\u0131ca, bir ki\u015finin sonu\u00e7ta Parkinson hastal\u0131\u011f\u0131na yakalan\u0131p yakalanmayaca\u011f\u0131n\u0131 belirleyen ek genetik veya \u00e7evresel fakt\u00f6rlerin neler oldu\u011funu anlamak i\u00e7in daha fazla ara\u015ft\u0131rmaya ihtiya\u00e7 oldu\u011funu da kabul etti.<\/p>\n\n\n\n

Karde\u015f haber kaynak:https:\/\/checkinhaber.com\/2026\/04\/21\/karnimizdaki-kucuk-rehberler-zihinsel-dejenerasyonun-izini-suruyor\/<\/a><\/p>\n\n\n\n

G\u00f6rsel Kaynak: https:\/\/i.gazeteoksijen.com\/2\/850\/478\/storage\/files\/images\/2026\/04\/21\/bagirsak-sagligi-0t3f.png<\/a><\/p>\n\n\n\n

Kaynak: https:\/\/gazeteoksijen.com\/saglik\/bagirsak-bakterileri-parkinsonu-yillar-oncesinden-fisildiyor-olabilir-272989<\/a><\/p>\n\n\n\n

https:\/\/gazeteoksijen.com\/saglik<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

21.04.2026 21:25 \u0130ngiltere merkezli akademik bir kurumun y\u00fcr\u00fctt\u00fc\u011f\u00fc incelemeler, sindirim sistemindeki mikrobiyolojik dizilimlerin, sinirsel tahribat hen\u00fcz g\u00f6zlemlenmeden \u00e7ok uzun zaman evvel bu duruma dair i\u015faretler verebilece\u011fini kan\u0131tlad\u0131. Bilim insanlar\u0131, ba\u011f\u0131rsak bakterilerindeki belirgin kal\u0131plar\u0131n Parkinson hastal\u0131\u011f\u0131 belirtileri ortaya \u00e7\u0131kmadan y\u0131llar \u00f6nce bu hastal\u0131\u011fa yakalanma riski ta\u015f\u0131yan ki\u015fileri belirleyebilece\u011fini ke\u015ffetti. Kar\u0131n B\u00f6lgesi Refah\u0131, Zihinsel Fonksiyon Kay\u0131plar\u0131n\u0131n Seyrini…<\/p>\n","protected":false},"author":5,"featured_media":6918,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[12],"tags":[2164],"class_list":["post-6917","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik","tag-bagirsak-bakterisi"],"jetpack_featured_media_url":"https:\/\/dbsnewsmedia.com\/wp-content\/uploads\/2026\/04\/44.png","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/posts\/6917","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=6917"}],"version-history":[{"count":1,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/posts\/6917\/revisions"}],"predecessor-version":[{"id":6919,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/posts\/6917\/revisions\/6919"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=\/wp\/v2\/media\/6918"}],"wp:attachment":[{"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=6917"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=6917"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dbsnewsmedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=6917"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}